Mutation Detection Using Spinal Tap May Help Monitor CNS Lymphoma
The MYD88 driver mutation was detected in the cerebrospinal fluid of a majority of patients with CNS lymphoma, indicating its potential utility as a diagnostic and monitoring tool.
Does Adjuvant Therapy Affect Quality of Life in Resected Melanoma Patients?
In this patient-reported outcomes analysis of the COMBI-AD study, researchers looked at the health-related quality of life in those with resected stage III melanoma with BRAF mutations.
Cutaneous Toxic Effects of Anti–PD-1 Therapy May Signal Improved Response in Melanoma
Researchers looked at the outcomes of patients who experienced cutaneous toxic effects after treatment with anti–PD-1 therapy for advanced melanoma compared with patients who did not.
Combo Immunotherapy Failed to Improve Outcomes in MSS Colorectal Cancer
A phase III trial examined immunotherapy in patients with microsatellite-stable metastatic colorectal cancer.
Does Occupational Pesticide Exposure Lead to Treatment Failure for DLBCL?
Researchers looked at the treatment failure rate for immunotherapy with R-CHOP in patients with diffuse large B-cell lymphoma who were occupationally exposed to pesticides.
Implementing a Toxicity Screening Form to Report Chemo Side Effects
The number of patients reporting side effects related to chemotherapy increased by more than 40 percentage points after the implementation of a chemotherapy toxicity screening form.
Men Open to Starting Physical Activity Prior to Prostate Cancer Treatment
The researchers explored implementation of physical activity for men recently diagnosed with prostate cancer to see which interventions will be best sustained over time.
Using the THRIVE Program to Teach Self-Care to Oncology Nurses
The THRIVE Program includes an 8-hour retreat designed to teach staff skills for combating compassion fatigue and for promoting resilience.
Nurse-Led Prostate Cancer Clinic Examines Patient Anxiety
The clinic educates, evaluates, and guides patients with prostate cancer on available treatments and helps to control associated anxiety.
Role of Oncology Nurses in Primary Palliative Care Growing
Oncology advanced practice registered nurses can play a critical role in providing primary palliative care to patients with cancer.
PRIMA-PI Risk Score for Follicular Lymphoma Promising for Trials, Clinical Practice
Researchers compared the newly developed PRIMA-PI risk score against FLIPI and FLIPI-2 in patients with follicular lymphoma.
CD38-Targeting Isatuximab Combo Active in Refractory Myeloma
Researchers tested the combination of isatuximab with dexamethasone and pomalidomide in patients with relapsed or refractory multiple myeloma.
Primary Radiotherapy Plays Important Role in Early Follicular Lymphoma
A retrospective study supported the role of primary radiotherapy in early-stage follicular lymphoma.
New CAR T-Cell Therapy for Multiple Myeloma Targets GPRC5D
Researchers have identified a potential new target for CAR T-cell therapy in patients with multiple myeloma.
Examining Opioid-Related Hospitalizations for Patients With Cancer
Researchers looked at the trends and risk factors for opioid-related hospitalizations among patients with cancer.
Adopting Clinician Training to Prompt Comprehensive End-of-Life Conversations
A series of communication-focused interventions were implemented to try to improve conversations about values, goals, and preferences with patients with life-limiting cancer.
A Look at the Clinical Benefits of the FDA’s Expanded Access Program
A single-center evaluation of the FDA's Expanded Access program indicated broad use of the program among the center’s patients, including a large percentage of pediatric patients.
Drug Combo Granted Priority Review for Untreated Follicular Lymphoma
The FDA has granted Priority Review to Celgene’s application for lenalidomide in combination with rituximab for previously untreated follicular lymphoma.
Subcutaneous Daratumumab vs IV Formulation in Relapsed Multiple Myeloma
The phase III COLUMBA study compared a subcutaneous formulation of daratumumab vs the intravenous form in patients with relapsed or refractory multiple myeloma.
Could Robotic-Assisted Surgery Reduce Complications for Endometrial Cancer Patients?
Researchers studied the use of minimally invasive robotic surgery for hysterectomy and its risk for complications in the treatment of endometrial cancer in Denmark.
Is WBRT or ASCT Better Consolidation for Younger Patients With CNS Lymphoma?
The PRECIS study looked at consolidation treatment with autologous stem cell transplantation vs whole-brain radiation therapy in younger patients with CNS lymphoma.
Scoring System Could Guide Decisions in Transplant-Ineligible Myeloma
Researchers have developed and validated a clinical scoring system that could help guide treatment decisions among patients with multiple myeloma.
‘Real-World’ Follicular Lymphoma Study Examines the Negative Effect of Early Progression
Researchers examined the effect of early progression in a real-world setting of follicular lymphoma patients.
Oral Duvelisib Potential New Option for Indolent Non-Hodgkin Lymphoma
The DYNAMO study investigated the oral PI3K gamma inhibitor duvelisib in heavily pretreated indolent non-Hodgkin lymphoma patients.
HSD3B1 Variants Linked With Outcomes of Prostate Cancer Treatments
Researchers found that the HSD3B1 genotype may be a predictive biomarker for the use of certain prostate cancer therapies.
Ofatumumab Shows Limited Activity in Previously Untreated Follicular Lymphoma
In this study, single-agent ofatumumab did not show superiority to rituximab or obinutuzumab, raising the question of whether ofatumumab should have a role in the treatment of follicular lymphoma.
Impressive Results Seen With Drug Combo in High-Risk Follicular Lymphoma
The final results of the LNH-PRO-05 study showed that a combination of antiproliferative and immunomodulatory agents with chemo had good outcomes in follicular lymphoma patients.
Ibrutinib/Nivolumab Combo Shows Promise in Richter’s Transformation
The combination of ibrutinib and nivolumab showed promising clinical response in patients with Richter’s Transformation.
Aurora A Kinase Inhibitor vs Standard Treatment for PTCL
Is Aurora A kinase inhibitor alisertib superior to standard treatment protocol for peripheral T-cell lymphoma?
Second AHCT, RVD Consolidation Post-AHCT Intervention in Myeloma?
A study investigates the efficacy of a second AHCT or RVD consolidation post-AHCT intervention in transplantation-eligible myeloma patients with multiple myeloma.