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Lung Cancer Targets

Study Identifies How Lung Tumors Acquire Immunotherapy Resistance

NSCLC can acquire resistance to immune checkpoint blockade agents through evolutionary culling of tumor clones harboring the mutations for cell surface neoantigens that are recognized by patients’ immune T cells. Image © Tashatuvango/ Shutterstock.com

Image © koya979 / Shutterstock.com

Lung Cancer Targets

An IHC assay for ALK status in non-small cell lung cancer tumor tissue predicts crizotinib treatment outcomes and offers a rapid and potentially less expensive alternative to older FISH ALK status assays.

A study just published in Cancer Cell is suggesting a new target for combating KRAS-mediated lung adenocarcinoma.

In my practice, I am constantly being asked how to properly treat scalp involvement in relation to these skin toxicities.

Among active or former smokers undergoing lung cancer screening, longer peripheral leukocyte telomere length is associated with an increased risk of lung cancer.

Non-small cell lung cancer can acquire resistance to immune checkpoint blockade agents through evolutionary culling of tumor clones harboring the mutations for cell surface neoantigens that are recognized by patients’ immune T cells.

A 38-year-old woman presents with multiple pulmonary nodules. After further assessment a biopsy is performed. What is your diagnosis?

Researchers at UC San Francisco have recently discovered genetic mutations in a protective protein called Capicua (CIC). The scientists demonstrated that there is a disproportionate frequency of mutated CIC in human lung cancers that have metastasized.

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