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Managing Bortezomib-Induced Neuropathy

In this article, we discuss a common and painful side effect associated with cancer treatment.

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Of the 39 advanced gastric cancer patients treated with the immunotherapy antibody, pembrolizumab (Keytruda, Merck), 22.2% had an objective response. The median time to response was 8 weeks and the median progression-free survival (PFS) was 1.9 months

The PD-1 inhibitor nivolumab increased progression-free and overall survival compared with chemo in patients with previously untreated metastatic melanoma.

No difference in anxiety was found among patients with non-Hodgkin lymphoma who were assigned to maintenance rituximab compared with those patients who were assigned to rituximab re-treatment upon disease progression, results of a recent study show.

Researchers at the Walter and Eliza Hall Institute of Medical Research in Melbourne, Australia, have discovered a protein that could help treat certain lymphomas, including those resistant to therapy.

For patients with metastatic clear cell renal cell carcinoma (mccRCC), administering a sequential, second-line tyrosine kinase inhibitor (TKI) may be more beneficial over a mammalian target of rapamycin inhibitor (mTORi).

A drug used to treat amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease), is also helping to boost the effectiveness of radiation for those melanoma patients with metastasis to the brain.

A mechanism that leads to resistance to certain targeted therapy drugs for melanoma has been discovered by researchers at the Moffitt Cancer Center in Tampa, Fla.

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