Identifying gene signatures in patients with clear cell renal cell carcinoma (ccRCC) that can predict the likelihood of their disease metastasizing, as well as the site of metastasis, may help to better stratify risk assessment for the disease and plan appropriate treatment strategies.
It seems as though we are seeing more news reports lately on the rising cost of cancer drugs—specifically targeted therapy drugs. Some are even going as far as to ask cancer patients and survivors to sign a petition in hopes of lobbying Congress so that government officials can negotiate lower prices with pharmaceutical companies.
In a study with mice and cells taken from human patients with B-cell precursor acute lymphoblastic leukemia (BPL), a combined molecule involving the CD19 receptor and a protein called sTRAIL, showed potent anti-leukemic activity. The “fusion protein” created was far more potent than sTRAIL alone.