Age, Cancer Type May Determine Tumor Mutation Load
A new study has found that high tumor mutation load is associated with older age, absence of oncogenic mutations, and presence of tumor suppressor gene mutations.
Brigatinib Offers Disease Control in Crizotinib-Refractory NSCLC
Higher doses of the kinase inhibitor brigatinib as second-line therapy for ALK-positive non–small-cell lung cancer may be an option for some patients.
Self-Renewing Hematopoietic Stem Cells May Benefit Leukemia Patients
Researchers at Weill Cornell Medicine are reporting that they have successfully converted cells from blood vessels in mice into blood-forming stem cells.
Prostate Cancer Subtyping May Lead to More Personalized Care
A study may be able to identify which men with aggressive prostate cancer will benefit from androgen deprivation therapy.
Mapping the Genetic Changes Driving Glioblastoma
Researchers have now mapped genetic changes that help drive glioblastoma and are hoping this will lay the foundation for targeted treatment of the disease.
Improving CAR T-Cell Immunotherapy in Children, Young Adults
Researchers at Seattle Children's Research Institute announced the first-in-human clinical trial aimed to extend remission for children and young adults with leukemia treated with CAR T-cell immunotherapy.
Manipulating DNA Repair Crews to Combat Cancer
Researchers from Johns Hopkins University report on a cascade of events that appears to correlate with early cancer recurrence and decreased overall survival.
Subcutaneous Rituximab May Soon Be Approved for Certain Blood Cancers
A new study is suggesting that intravenous and subcutaneous rituximab share similar efficacy and safety profiles.
Recurrence of Head and Neck Cancer Associated With PD-L1 Expression
A new study is suggesting there may be an association with high tumor levels of the protein PD-L1 and head and neck disease recurrence.
New Study Offers Insights Into Intratumoral Cancer Cell Intravasation
California researchers think they may have discovered why some cancers may reoccur after years in remission.
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