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Skin Cancer / Melanoma Targets

Skin Cancer / Melanoma Targets

The UV radiation resistance-associated tumor suppressor gene coordinates DNA repair and might predict skin cancer risk, according to research published in the journal Molecular Cell.

It now turns out that Bim, a downstream signaling molecule of the PD-1 pathway, may hold the clue to which patients may be successful on immunotherapy for metastatic melanoma.

Induced pluripotent stem cells (iPSC) may provide an unlimited number of phenotypically defined, functional and expandable autologous antigen-specific T cells with the characteristics needed to combat cancer.

A 37-year old man presents with a bluish lesion in the right arm. After further assessment, a biopsy is performed. What is your diagnosis?

Patients with metastatic Merkel cell carcinoma treated with pembrolizumab (Keytruda, Merck) as a first-line therapy had durable responses in a phase II clinical trial.

More than one-third of patients with advanced melanoma were still alive 5 years after starting treatment with the anti-PD-1 immunotherapy nivolumab, according to long-term phase I data.

Researchers at the University of Colorado Cancer have created a new tool that will help oncologists match the right therapy to cancer type based on the patient's genetic data.


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