The UV radiation resistance-associated tumor suppressor gene coordinates DNA repair and might predict skin cancer risk, according to research published in the journal Molecular Cell.
Skin Cancer / Melanoma Targets
It now turns out that Bim, a downstream signaling molecule of the PD-1 pathway, may hold the clue to which patients may be successful on immunotherapy for metastatic melanoma.
Induced pluripotent stem cells (iPSC) may provide an unlimited number of phenotypically defined, functional and expandable autologous antigen-specific T cells with the characteristics needed to combat cancer.
A 37-year old man presents with a bluish lesion in the right arm. After further assessment, a biopsy is performed. What is your diagnosis?
Patients with metastatic Merkel cell carcinoma treated with pembrolizumab (Keytruda, Merck) as a first-line therapy had durable responses in a phase II clinical trial.
Researchers at the University of Colorado Cancer have created a new tool that will help oncologists match the right therapy to cancer type based on the patient's genetic data.
Neutralizing intratumoral pH may help improve responses to immunotherapy and improve outcomes with current targeted therapies, according to a study published March 15, 2016, in the journal Cancer Research.
A research team at University of California, Merced has identified a drug that could be effective in targeting melanoma cells.
A 90-year-old woman presents with a lesion in the right forearm. After further assessment, a biopsy is performed. What is your diagnosis?
PRAME mRNA is a biomarker of metastasis risk for patients with class 1 uveal melanoma, according to authors of a retrospective study.