Scientists from the Ohio State University (The James) Comprehensive Cancer Center and Perlmutter Cancer Center of NYU School of Medicine have found an association between genes linked to eye color and development of uveal melanoma.
Skin Cancer / Melanoma Targets
A new study is suggesting that it may be possible to turn melanoma into a nonthreatening, easily curable disease.
A 47-year-old man presents with an “atrophic” lesion of the skin in the right arm. After a biopsy is performed, what is your diagnosis?
Immune response markers from on-treatment—but not pretreatment—melanoma biopsies predict responses to immune checkpoint blockade.
Patients with metastatic melanoma may benefit from the addition of a local tumor-targeted treatment in addition to ipilimumab.
Obtaining blood biopsies instead of invasive tissue biopsies may be less risky for patients, faster, and cost less.
Along with gene expression signatures from a 15-loci panel, tumor diameter and specific driver mutations predict metastasis risk and survival among patients with uveal melanoma.
In this video we discuss 3-year overall survival data from the KEYNOTE-001 trial, which studied the anti–PD-1 antibody pembrolizumab in patients with advanced melanoma.
Inflammatory arthritis and sicca syndrome appear to be immune-related adverse events among some patients undergoing cancer treatment with the immune checkpoint inhibitors nivolumab and ipilimumab.
Trametinib, which is approved by the FDA for melanoma and other cancers, may block viral infection by stopping Merkel cell polyomavirus transcription and replication.